Mice are highly social animals that make excellent pets for children if properly cared for. They are timid, but if they are raised as pets and gently handled, they will rarely bite. The average lifespan for a pet mouse is 1-2 years.


Cage – Each mouse requires a minimum of 15 square inches of floor space and at least a height of 5 inches. Cage material can include wire, stainless steel, or durable plastic/glass. Wood and thin plastic are discouraged because mice like to chew. At least 1 side of the enclosure must be open for air circulation. Cage bottoms should be solid as wire or mesh bottoms can irritate feet.

Substrate – Deep bedding (at least 1 inch) with ample nesting material is recommended. Bedding must be clean, non-toxic, and absorbent. Paper pulp products (Carefresh or Yesterday’s News), shredded newspaper or shredded computer paper are recommended. Wood chips and shavings (especially cedar and pine) are NOT recommended as they can cause respiratory disease.

Nesting Material – Mice like to construct nests to sleep in. Cotton and shredded tissue paper are suitable for nesting material.

Furniture – Cage furniture (exercise wheels, tunnels, hide boxes, etc) is highly recommended for enrichment and play. Small cardboard boxes, paper towel rolls, tissue boxes, etc. can be used as hiding boxes.

Temperature – The optimal temperature for mice is between 65-80°F.

Cage mates – Mice can either be housed as individuals, in same-sex pairs, or in small groups. Fighting can occur and close monitoring is necessary. Spaying and neutering is recommended in mixed gender groups. There should be multiple food and water sources in group cages. If mice are kept individually, they should be handled every day.

Cleaning – The cage and all accessories should be cleaned at least once a week with hot water and a non-toxic disinfectant or detergent, then rinsed thoroughly.


Mouse food/rodent blocks – A complete and fortified food should be offered “free-choice.” We recommend the Oxbow Essentials Mouse and Young Rat diet. Do not feed mixes containing seeds, dried fruits, or nuts as mice will preferentially consume the seeds/fruits/nuts that are high in fat and low in other nutrients and can lead to obesity and malnutrition.

Treats – Small pieces of fruits, vegetables (romaine, bib and red leaf lettuce, parsley, and cilantro), table food, or seeds may be offered. Grass hay can be used to stimulate foraging activity. Oxbow also makes a variety of healthy treats for mice.

Water – Clean water should be provided in sipper bottles or a spill-proof bowl. Water should be changed daily.

Cleaning – Bowls and water bottles should be cleaned every few days in the dishwasher or with a dilute bleach solution (1:30 bleach to water ratio) soak.


Pet mice become accustomed to handling and will seldom bite if properly restrained. They can be picked up by scooping them up. Always use two hands and be gentle. Avoid sudden movements, loud noise, and excitement. Do not pull on the tip of the tail. If children are handling the mouse, have them sit on the floor and hold it in their laps. Only allow them to handle the pet with adult supervision.


We recommend a complete physical exam and fecal by an exotic animal veterinarian for all newly acquire pet mice. Thereafter, we recommend bi-annual exams and yearly fecal exams.

Spaying and Neutering – This procedure is recommended at 6 months of age to help decrease the incidence of mammary tumors as well as aggression among cage mates.


Respiratory disease – Respiratory infections are very common in mice and should be treated right away as the infection could develop into pneumonia. Symptoms include sneezing and nasal discharge.

Lice and Mites – Skin parasites are common in new pets. Symptoms include itching, red skin, hair loss, and irritability.

Wounds – Mice housed in pairs or groups can fight and often will result in deep wounds.